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To address the possibility that altered Kirrel-2 and Nrp1 levels in dnRAR mice were caused by altered expression of proteins mediating sensory transduction in OSNs, we analyzed for Gαolf, AC3, and CNGA2.
Those changes may be mediated by altered expression of NMDAR subunits and sonic hedgehog.
Generally, deregulation of this hierarchy might be caused by altered expression of certain oncogenes or loss of tumor suppressor genes (TSGs).
Reduction in induced pain by ultrasound may be caused by altered expression of spinal neuronal nitric oxide synthase-producing neurons.
These changes in spine density were accompanied by altered expression of proteins known to interact with PSD-95, including NR2B and SAP102, suggesting that PSD-95 plays a role in regulating the expression and activation of proteins found within the NMDA receptor complex.
In particular, tumor microenvironments are highly angiogenic and are characterized by altered expression of pro-angiogenic matricellular proteins.
These reports showed that transcript levels of clpP1, clpP2 and clpC were modulated by altered expression of Rv2745c.
Therefore the deficient Th1 function of LPS stimulated MoDC from HCV patients could not be explained by altered expression of these surface markers of DC.
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A further indication of impaired translation during aging is provided by altered expression levels of ribosomal proteins, of which we identified three (RPS5, RPS6, RPS29) in our study.
Notably, it is not only the expression of IL-1 and TNF-α that is increased in the degenerate IVD [ 13, 15]; the cellular response to stimulation is altered [ 15, 18], as is the sensitivity of the cell population, evidenced by altered expression patterns of the receptors [ 13, 15, 16].
Additionally, biosynthesis of fatty acid is likely, at least in part, to also be regulated by NPY neuron specific Y2 signalling, as evident by altered expression levels of acetyl-CoA carboxylase (ACC) in skeletal muscle of female mice, which could subsequently inversely influence expression of CPT1.
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by altered specificity of
by altered variability of
by altered function of
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by altered ubiquitination of
by altered variability of
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by public expression of
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