Sentence examples for by alterations in expression from inspiring English sources

The metabolic changes highlighted by alterations in expression levels of DAF-16 target genes underscore the lower energy reserves present in exposed worms.

We did not observe any compensation by alterations in expression of the GSK3α isoform in the YFP+ cells of cre+GSK3βlox/lox mice (data not shown).

Further work tested whether changes in the relative expression of 5hmC at the Pdcd1 promoter expression was reflected by alterations in expression of mammalian Ten-Eleven-Translocation proteins.

Although a mechanism explaining this enhanced sensitivity with demethylation has not been elucidated experimentally, the role of these genes is closely linked at the G1/S transition phase of the cell cycle, and the subsequent fate of irradiated cells containing DNA damage at this point of the cell cycle would be influenced by alterations in expression of these two genes.

In contrast to that, in a recent publication, we demonstrated that primary tubular epithelial cells from a 7.5-week old PKD2 mutant 1-7033) tratsgenic rat, display increased proliferation accompanied by alterations in expression of Cdk2 and p57, but independent of p21 [ 26].

The phenotypic change of transformed cells was further supported by alteration in expression of genes during Cr VI) induced cell transformation.

Of note is the observation that neoplasia is associated not just with altered expression of SEPT9 but also by alterations in the expression of specific SEPT9 transcripts with the SEPT9_v4 transcript being predominant in normal tissues but being replaced by SEPT9_v4* in tumours (Burrows et al, 2003; Scott et al, 2005b).

The lack of heparanase expression and activity was accompanied by alterations in the expression level of MMP family members, primarily MMP-2 and MMP-14.

These differences were accompanied by alterations in mRNA expression of multiple functional gene groups.

The above mentioned phenotypic changes caused by telomere shortening in cancer cells are probably caused by alterations in gene expression.

In this regard, not only changes elicited directly by changes in Cldn6 signaling but also changes imparted by alterations in the expression of other Cldns, notably Cldn1, must be considered.