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All 11 NPAs from older children and adult (13 – 52 years) were negative for RSV by all three test methods.
The changes in gene expression were statistically significant by all three test compounds by 72 hours in MCF-7 cells and by 24 hours in ZR-75-1 cells.
Of the 9 BAL specimens, 6 were negative by all three test methods, 1 was positive by all three methods, and 2 were positive by DIF and cell culture, and negative by NOW RSV.
These molecular changes in both MCF-7 and ZR-75-1 cells by all three test compounds led us to infer that SXR can increase expression of p53 and several key p53 target genes associated with apoptosis and inhibition of cell proliferation in breast cancer cell lines.
Of the 27 NPAs from children aged 5 months to 5 years, 20 were negative by all three test methods, 2 were positive by all three methods, 2 were positive by NOW RSV and DIF, while 3 were positive by only DIF.
Similar(55)
The data were considered normal if found as normal by all three tests.
At day two, the amount of lactate accumulated was still about 30% higher by the cells with Fragment 9, whereas later, similar values were obtained by all three tested cell lines (Fig. 7C).
Positivity by all three tests was 32.5 %.
This minimum requirement is fulfilled by all three tested compounds.
15 of the 33 sequences proved to be negative for CC domains by all three tests.
Three known ovarian cancer genes (TP53, PTEN and CDKN2A) were identified by all three tests (convolution, likelihood ratio and Fisher's combined p-value tests) with a false discovery rate (FDR) of less than 0.10.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com