Sentence examples for by alignment to known from inspiring English sources

The M. anisopliae MAT1-1 alpha box domain [Pfam: PF04769] was confirmed by alignment to known MAT1-1 sequences and carries a conserved intron [ 22, 23].

The strategy for analysis of the sequencing data was to filter out reads derived from human genes, assemble the remaining reads into contigs, annotate these by alignment to known sequences and perform a phylogenetic classification.

Contig consensus sequences were identified as containing a putative full length coding sequence by alignment to known full-length protein coding sequences, and/or by the presence of stop codons upstream of a significant open reading frame.

miRNAs are often identified by cloning or by bioinformatic alignment to known miRNAs.

Transcripts were identified as PCWDEs based on amino acid alignment to known proteins.

The remaining two cases were relatively weak hits (108 and 103 bits) that were not captured by the alignments to known families.

Reads from an unknown genome are usually annotated according to their similarity (by alignment) to the known genomes.

The P1 promoter region of TP53 in the Bos taurus (domestic cow) genome was determined by transcript and EST analysis, and confirmed by alignment to the known TP53 promoterter in humans.

Finally, the short sequenced fragments (known as tags) are computationally mapped by alignment to a reference genome and regions of enriched tag counts are identified, a step known as peak-calling.

These conformations served as starting positions for further docking, each time selecting a peptide with similar or better ICM docking score and a superior binding conformation by backbone alignment to the known GSK3β peptide conformation.

Isoform-level alignment is also improved by alignment to CAST.