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Kater et al[29] had previously reported similar findings and suggested that warfarin exerts its anti-inflammatory actions by affecting the phosphorylation of I-κB.
SPARC also binds directly to growth factors such as VEGF and affects regulation of FGF by affecting the phosphorylation of the FGF receptor (Clark and Sage, 2008).
In a study on FER function using the Trojan peptide, researchers showed that FER that had dissociated from the cadherin complex could translocate to the integrin complex where it reduced p130CAS phosphorylation and interrupted integrin-mediated focal adhesion by affecting the phosphorylation of p130CAS binding partners, including PTP-PEST, PTP1B, FAK, and Crk [ 62].
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These results suggest that RCAN1 affected NF- κB activity by affecting the tyrosine phosphorylation of I κB α, which subsequently affected the NF- κB activity.
These findings suggest that the greater sensitivity of α1β2Lγ2L relative to α1β2Sγ2L toward current run-down is caused by the depletion of intracellular ATP affecting the phosphorylation status of Thr365.
We find that Lys49 acetylation is accompanied by increase in Ser45 phosphorylation without affecting the phosphorylation of the Ser33, Ser37, Thr41 sites.
18β-GA is an triterpenoid saponin that disrupts GP plaques by affecting the structural integrity, distribution, and phosphorylation of connexons.
Experiments were performed to determine whether the signaling pathways activated by TGF-α would affect the phosphorylation of YAP.
By contrast, Aβ oligomers do not affect the phosphorylation at S831 of GluA1.
We observed that MK-2206 minactivateivatEzrinin by affecting its phosphorylation at the T567 site in vitro as well as in vivo.
Thus, these data implied that transcript levels of STAT3 did not mirror protein levels, and Baicalin might regulate TH17 cell differentiation by affecting STAT3 phosphorylation but not the expression of STAT3.
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