Sentence examples for by affecting the interaction from inspiring English sources
The Tid1 mutation acts as a semi-dominant gene by affecting the interaction of alpha and beta tubulin.
Thus, by affecting the interaction of σ1Rs with NR1 subunits, σ1R antagonists regulate the activity of NMDARs.
In conditions in which autophagy is inhibited, Beclin-1 is inactivated by its interaction with Bcl-2, which functions as a brake to autophagy and autophagic cell death by affecting the interaction between Beclin-1 and Vps34.
In summary, our simulations suggest that B-cell depletion modulates autoimmune diseases mainly by affecting the interaction between Treg and Teff, and in particular strengthening the Teff-Treg cross-regulation by lowering the Treg activation threshold.
Indeed, a theoretical model by Givli and Bhattacharya (Givli et al., 2012), explicitly introducing osmotic pressure contributions within the generalized Helfrich energy treatment, suggests that pressure can perturb isothermal phase diagram, driving domain formation primarily by affecting the interaction between geometry and composition.
They could also play a more specific regulatory role, by affecting the interactions of the functional promoter with regulatory proteins, or by causing the transcription complex to pause after initiation during the early steps of elongation.
Thus, uPA might serve a physiological role during TNF-induced apoptosis by affecting the interactions between cells and the basal membrane, thereby facilitating anoikis.
Our findings suggest that benazepril decreases ILK and α-SMA expression, at least in part, by affecting the interactions between Ang II and TGF-β1.
It is, therefore, possible that this particular mutation exerts its effect by disrupting the conformation of the full-length protein, perhaps via intra-molecular interactions between domains, or by affecting the interactions with a putative co-regulator.
In E. coli, it has been shown that mutations in these three consecutive G bases reduce the efficiency of initiation of protein synthesis, by affecting the interactions between the tRNA and the ribosomal P site; thus, these bases are essential to discriminate between initiator and elongator tRNA-Met [ 9, 20].
The regulation of vascular tone may be impaired by changes affecting the interaction between these vascular cells [ 131].
