Sentence examples for by affecting the binding from inspiring English sources

Loss of such a CpG-rich region could affect transcription not only through the removal of DNA methylation, but also by affecting the binding of other regulatory proteins in that region [46].

The analysis suggested that rs6983267 interacted with aspirin by affecting the binding of TCF7L2 in an allele-specific way.

Lowe et al. propose a model for how RanGTP may control the flow of cargo through the nuclear pore by affecting the binding of importin-β to Nup153.

We hypothesized that these alleles might have causative roles by affecting the binding of proteins and thus the regulation of transcription of aromatase in the brain.

Furthermore, diverse substances have been reported to interfere with the ThT assay, either by quenching the fluorescence or by affecting the binding of ThT to amyloid structures.

These findings indicated that rs1057035 located at 3′UTR of DICER may contribute to the risk of oral cancer by affecting the binding of miRNAs to DICER.

Thus, the Hpx domain in the C-terminal region maintains the specificity of collagenase family MMPs by affecting the substrate binding [2].

By affecting the Hand1 binding site in the promoter, this cis-SNP could be responsible for differential expression of Casc4 in the BXH F2 population.

Sulphation of these structures can modulate the activity of these molecules by affecting the kinetics of binding [ 26] and increases their rate of clearance from the body [ 27].

Therefore, we speculated that those two genetic variants are associated with SLE by affecting the transcription factors binding in their located enhancers.

Current information about transcription factor binding site sequence patterns may not be exhaustive, and SNPs may be actively involved in influencing gene expression by affecting the transcription factor binding sites.