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But natural selection requires random variation to generate the various properties.Retrotransposons could provide that variation, by affecting gene expression at random, depending on where they pitch up.
Thus, G9a might play a critical role in regulating centrosome duplication, presumably through chromatin structure rather than by affecting gene expression in cancer cells.
As for most other polyQ diseases, conformational changes imparted by the expanded polyQ tract lead to the formation of neuronal intranuclear inclusions (NIIs) [13] and may contribute to pathogenesis by affecting gene expression [14] or by disrupting nuclear organization and function [15].
Increasing evidence indicates that chromatin remodeling mediates hematopoietic cell fate decisions by affecting gene expression 15.
Six operate by affecting gene expression and chromatin remodeling as we briefly review here.
Thus, the hTERT-VNTR2-2nd locus may function as a modifier of prostate cancer risk by affecting gene expression.
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Bcl2 can enhance maturation by directly affecting gene expression, as shown for the hematopoietic differentiation of murine embryonic stem cells.
MicroRNAs (miRNAs) are a new class of small, endogenous RNAs that play a regulatory role in the cell by negatively affecting gene expression at the post-transcriptional level.
MicroRNAs (miRNAs) are small, endogenous RNAs that play important regulatory roles in development and stress response in plants by negatively affecting gene expression post-transcriptionally.
These microRNAs results support the role played by zinc in affecting gene expression at the posttranscriptional level.
It may be hypothesized that impaired glycolytic metabolism at birth, which is essential to ensure body thermoregulation, has been affected by genetic selection, affecting gene expression between breeds [ 37– 37].
More suggestions(16)
by affecting gene sequence
by affecting gene exposure
by regulating gene expression
by affecting gene methylation
by affecting gene environment
by affecting gene gene-expression
by affecting gene integrity
by affecting gene transcription
by affecting gene analysis
by affecting gene remodeling
by prolactin gene expression
by affecting gene binding
by affecting gene accessibility
by optimizing gene expression
by modulating gene expression
by analyzing gene expression
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