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When applied in screening phase, zebrafish bioassays aimed to identify active fractions by organism-level endpoints, which were later further investigated by additional methods with zebrafish [52] or with other experimental models [19,45].
The HSQC-based database is a fast and cost-effective way of accumulating information about a huge number of standard compounds, although further specific analyses of NMR-based atomic assignments using NMR spectra obtained by additional methods such as COSY or total correlation spectroscopy (TOCSY) are required.
For all of these reasons, validation by additional methods is critical.
In contrast, a much lower prediction confidence of 78.9% was obtained in the LC region, indicating that these predictions need to be further verified by additional methods.
While data triangulation via the collection of data by additional methods (e.g. interviews) would have been ideally realized, such inclusion was not logistically feasible.
But the generation of cell type-specific surface antibodies is challenging, and optimization of cell purification strategies would be enhanced by additional methods to identify, isolate, and remove pluripotent cells.
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However the use of the mean rank is itself problematic as the pairwise similarity of two methods can be altered (and even inverted) by adding additional methods to an evaluation.
Copy number was estimated by two additional methods.
We modified Morse's definition of QUAL- qual methods [ 26] by including additional methods and continued to categorize all of these as being core or supplement.
It is therefore desirable to extend the software by implementing additional methods that do enable the joint consideration of a larger number of SNPs in LD.
We show that, instead of taking the first haplotype inference reported by the program, we can significantly improve the quality of the final result by applying additional methods that include scoring of the alternative haplotype inferences and genotype optimisation.
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