We have clarified it by adding the following sentence to the figure legend: "Instead of using mitoGFP, we utilized anti-ATPase antibody, which allows better visualization of the enhancement phenotypes seen with double mutants".
We have expanded our discussion of known WaaL substrate specificity by adding the following sentence: "In E. coli the multitude of different O-antigens initiate with GlcNAc, ECA also initiates with GlcNAc.
We have tried to acknowledge it by adding the following sentence to the Results section: "However, despite the small P-values, some of the associations may be false positives because the minor allele frequency cut-off of the DGRP Freeze 1 algorithm was 4 lines, allowing the P-value to be driven by a few extreme lines".
This is an important point, which we have addressed by adding the following sentence to the Discussion where we consider the potential generality of our observations: "However, when assessing the significance of such effects it is also important to consider how outcrossing versus selfing will influence patterns of homozygosity and heterozygosity within species".
One interpretation would be that, by adding the new first sentence, Congress changed the meaning of the second sentence of the definition to conform to the new first sentence, without altering the words.
To clarify the different extents of suppression by scSUI1, we added the sentence: "Introducing scSUI1 also mitigated their Slg- phenotypes, slightly for - R225K and substantially for - E144R".
We have clarified our rational for looking at activity enhancing mutations by adding these sentences to the results section: "Our ability to link protein folding to antibiotic resistance gives us a unique opportunity to select for activity enhancing mutations in a chaperone.
The court also made a prospective suggestion, saying that a sensible way to avoid Vienna Convention problems is to alert foreigners to their rights by adding a sentence to the standard Miranda warning.
We have clarified this by adding a sentence in the corresponding figure legends and by stating which type of preparation (whole sperm cell vs flagellum were used).
We have clarified this point by adding a sentence to the Results section stating that pol V and ago4 mutants most likely affect P4R2 and siRNA levels indirectly via their involvement in DNA methylation and histone modifications that have been shown to recruit Pol IV to target sites.
