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Replacement of H4monoK20 with H4diK20 in response to Myc activation should be accompanied by activation of specific histone methyltransferases.
To ascertain that OXT-evoked responses were mediated by activation of specific receptors, we tested the effect of L-371,257, an OXTR-selective antagonist [35].
Additionally, exposure to cold will stimulate heat production in mitochondria [16] by causing protons to pass through the inner membrane without ATP production, which is facilitated by activation of specific uncoupling proteins (uncoupling protein 1 or UCP1).
By activation of specific downstream effector molecules, these receptors induce a variety of cellular responses many of them central to tumor biology [8] including cell transformation, survival, migration, metastasis, and angiogenesis [3,8 11].
In one, cytoplasmic aggregates of TDP-43 are toxic, leading to altered neuronal function or survival by interfering with basic cellular function or by activation of specific cell-death pathways.
NPD1's action on TRPV1 is likely mediated by activation of specific pertussis toxin-sensitive/G αi-coupled GPCRs and subsequent inhibition of adenylyl cyclase, PKA, and ERK signaling pathways.
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Engagement of TLRs to their appropriate ligands is followed by activation of a specific sequence of protein tyrosine kinases, mitogen-activated protein kinases and extracellular-activated receptor kinase molecules.
Our data suggest that the upregulating cellular uptake in breath-hold diving is not caused by activation of the specific glucose transporters.
The increase of insulin blood value during breath-hold diving associated with the decrease of glycemia confirms that the upregulating cellular uptake is not caused by activation of the specific glucose transporters GLUT4.
The increase in blood insulin during BH-diving associated with the decrease of blood glucose levels could indicate that the upregulating cellular uptake is not caused by activation of the specific glucose transporters.
The increase of insulinemia during BH-diving associated with the decrease of glycemia could indicate that the upregulating cellular uptake is not caused by activation of the specific glucose transporters GLUT4, even if the complex changes caused by hyperbaric exposure do not permit to exclude that other mechanisms are involved in addition to the pilot role of insulin.
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by activation of myeloid
by way of specific
by determination of specific
by comparison of specific
by recruitment of specific
by activation of AMP-activated
by provision of specific
by consideration of specific
by addition of specific
by incorporation of specific
by alleviation of specific
by acquisition of specific
by introduction of specific
by detection of specific
by activation of p38MAPK
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