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The goal of this study was to determine when during lineage progression ObL cells are susceptible to an AdL fate switch by activation of endogenous peroxisome proliferator-activated receptor (PPAR)γ.
Does MKL1/2 engage a RasGAP (RasGTPase activating protein) that causes senescence by activation of endogenous Ras and Ras effector pathways?
Therefore, further studies are required to determine whether the implanted TEC contributed to cartilage repair directly by local differentiation to chondrocytes or indirectly via release of mediators which enhance repair by activation of endogenous chondrocytes or activation and differentiation of other cells in the intra-articular environment.
This process is accompanied by activation of endogenous Sox2 expression.
Biochemically, apoptosis is characterized by activation of endogenous nucleases and DNA degradation into fragment multiples of 185 bp [ 24] which we observed in the DNA fragmentation assay.
However, this requirement is during the final phase of reprogramming when other key factors are already present and may be fulfilled by activation of endogenous Nanog.
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In fact, Nanog is probably essential to obtain fully reprogrammed iPS cells, but this requirement may be fulfilled by activation of the endogenous gene (Okita et al, 2007; Silva et al, 2009).
This effect could be mediated by the activation of endogenous channels by the toxin or by the toxin itself.
In the literature, MSCs are described to home to injured areas and regenerate damaged tissue by either causing cytoprotection, anti-inflammation or by inducing activation of endogenous stem cells (Gnecchi et al., 2012; Siegel et al., 2012; Williams & Hare, 2011).
Cellular levels of ROS are increased by UV activation of endogenous photoreceptors in the cell.
UV induces various types of DNA damage either photochemically or by UV activation of endogenous photoreceptors that create genotoxic free radicals that modify the DNA molecular structure.
More suggestions(15)
by activation of co-stimulatory
by activation of myeloid
by expression of endogenous
by alteration of endogenous
by modulation of endogenous
by recognition of endogenous
by secretion of endogenous
by activation of AMP-activated
by activation of lexical
by activation of uninfected
by number of endogenous
by incorporation of endogenous
by activation of p38MAPK
by activation of c-Jun
by quenching of endogenous
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