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Their role in abiotic stress adaptation by activation of different signaling pathways is emerging.
We show that subpopulations of human astrocytes, generated by activation of different signaling pathways in the same population of human glial precursor cells, have markedly different effects when transplanted into the injured spinal cord.
The proteolysis of BAMBI can be enhanced by activation of different forms of autophagy, such as macroautophagy induced by serum starvation, or by alternative forms of autophagy activated by rapamycin.
Physiological responses following the signal transduction are regulated by activation of different transcription factors.
After implantation, transvenous device leads usually undergo fibrotic encapsulation by activation of different cellular and humoral mechanisms.
Experiments performed on human tumor cell lines demonstrated that morphine in high concentration induces apoptosis and inhibits cancer cell growth by activation of different signal pathways involving caspase 3/9 and cytochrome c, sigma-2 receptor.
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HGF-induced cell scattering and invasion is achieved by activation of several different signaling molecules and pathways, including PI3K, Rac and Rho [13],[13].
The seven members of the EGF family perform their functions by activation of four different high-affinity receptors, EGFR/ErbB1, HER2/ErbB2, HER3/ErbB3 and HER4/ErbB4 (Burgess, 2008).
We show here that intratumoral (IT) treatment with lipopolysaccharide (LPS), a TLR-4 agonist, significantly enhanced the local therapy induced by VSV by combining activation of different innate immune pathways.
This phenomenon of drug resistance or failure may be explained in part by the activation of different oncogenic pathways or de novo mutations that activate downstream molecules and increase signal transduction.
The vigor of motor output can be controlled by the graded activity of the same set of neurons [ 18], or by selective activation of different subsets of neuronal populations [ 19, 20].
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