Sentence examples for by activation of both from inspiring English sources

In contrast, the senescence response is an active process caused by activation of both DNA-damage responses (DDR) and mitogen-activated pathways.

In the thalamus, endogenous release of ACh by optogenetic stimulation results in a biphasic response caused by activation of both nicotinic and muscarinic ACh receptors56.

The chronic inflammation is in turn perpetuated by activation of both CD4+ and CD8+ T cells [ 10].

All four proteins interacted with MUPP1-PDZ10-13 as judged by activation of both the His3 and βgal reporter genes (Table 1).

In contrast, SynGAP1, TAPP1 and EphA7 all showed an interaction with LNX1 and/or LNX2, as judged by activation of both reporter genes.

RGC loss is accompanied by activation of both astroglia and microglia as indicated by significantly increased glial fibrillary acidic protein (GFAP) expression in the retinas of Opa1enu/+ mice.

Inspection of the transition graph (which represents the successive order of events) in m-xylene-high condition shows a progression of regulatory steps identical to the known activation itinerary of the TOL pathway i.e. both upper and XylS are expressed in response to XylR activation, followed then by activation of meta due both to 3 MBz formation and XylS hyperexpression.

Systemic inflammation is designated by activation of circulating cells of both the innate immune system, such as monocytes [ 3], and the adaptive immune system, such as CD4+ T-helper (Th) -lymphocytes, CD8+ -lymphocytes [ 4, 5], and CD19+ B -lymphocytes [ 6].

The morphological and biochemical features of apoptosis are caused by activation of caspase cascades in both of the major pathways, the death receptor-mediated extrinsic pathway and the mitochondria-mediated intrinsic pathway [ 2].

The p53 pathway is activated by transcriptional induction of alternate reading frame or by activation of ataxia teleangiectasia mutated protein, both of which suppress mouse double minutes mediated p53 degradation in the presence of DNA damage under genotoxic stresses (Di Leonardo et al. 1994; Herbig et al. 2004; Moiseeva et al. 2006; Taylor et al. 2004; Zhang et al. 2005).

Carnitine synthesis and uptake are both stimulated by activation of PPARα [30] and these measurements reflect a normal fasting response in both control and knockout animals.