Sentence examples for by activated forms of from inspiring English sources

In competition experiments, the acyltransferase was well inhibited by activated forms of fatty acids containing at least eight to fourteen carbons, but not by acetyl CoA.

2) Huang et al argued that Smurf-mediated ubiquitination and degradation of Ptc are promoted by activated forms of Smo (Smo SD ) in Drosophila (Huang et al., PLOS Bio 2013).

Death signals induced by anticancer drugs are transmitted from the mitochondria to downstream executioner caspases such as caspase-3, -7 and -6 and it is believed that cells succumb to death due to cleavage of several substrate proteins by activated forms of these executioner caspases.

Could they examine whether Ptch1Δ2 is degraded more or less effectively by Smurf than Ptch1 in the presence of Shh? 2) Huang et al argued that Smurf-mediated ubiquitination and degradation of Ptc are promoted by activated forms of Smo (SmoSD) in Drosophila (Huang et al., PLOS Bio 2013).

For instance, transgenic mice expressing an activated TGF-β type I receptor or dominant negative TGF-β type II receptor under control of the mouse mammary tumor virus promoter showed that TGF-β impairs mammary tumorigenesis induced by activated forms of the Neu receptor tyrosine kinase but promotes the formation of lung metastases [ 56].

The clinical efficacy of imatinib is well demonstrated in chronic myeloid leukaemia and in gastrointestinal stromal tumours (GISTs), which are driven by activated forms of BCR ABL and mutated KIT or PDGFRA genes, respectively (Druker et al, 2001; Demetri et al, 2002).

The cleavage of a sensor by activated form of the caspase 3 resulted in separation of two fluorescent proteins and elimination of FRET.

In order to correct this inconsistency we completed the model by introducing activated forms of nuclear receptors produced by physical interactions with other molecules.

These studies showed that genes regulated by the activated forms of Ras involve cellular processes associated with tumorigenesis.

ALDHs participate in multiple metabolic pathways and play a role in several cancerous disease states, including cancer chemoresistance, by metabolizing activated forms of oxazaphosphorine drugs.

Our finding that diminishing IGF-1R levels had stronger effects on IGF signaling in 129S2 than in B6 background suggested that signaling activity in this pathway is primarily determined by the prevalence of activated forms of receptor and substrates, but not by their total abundance.