Interestingly, RimP has previously been shown to accelerate binding of S5 and S12 by twofold and sixfold, respectively, in in vitro reconstitution assays (Bunner et al., 2010b).
Agonist-induced low-affinity conformation of the Gα G-protein subunit for GDP leads to accelerated dissociation of bound GDP that in turn accelerates binding of GTP and G-protein activation.
GTP-hydrolysis by GTPases is intrinsically slow but can be accelerated by binding of specific external factors.
Moreover, we have seen that osmostress strongly up-regulated the ARE binding protein TPP which has been shown to suppress inflammation by accelerating the decay of cytokine mRNAs upon p38 SAPK activation [ 20].
By accelerating the ability of cities to adapt and grow, we will accelerate our nation's economic growth and competitiveness.
by accelerating the joining of small contigs.
The RNA chaperone Hfq has been shown to be involved in accelerating the binding of some of these imperfectly binding sRNA:target pairs [7], [8].
The release of phosphate (Pi) is an important element in actomyosin function and has been shown to be accelerated by the binding of myosin to actin.
The free ADP-actin monomers can be readily recycled due to the inherently fast rate of nucleotide exchange of G-actin, and this step can be accelerated further by binding of profilin or Srv2 (Balcer et al. 2003; Chaudhry et al. 2010).
We describe an outbreak fueled by illicit drug use and characterized by accelerated progression of disease.
