Sentence examples for by abrogation from inspiring English sources

These data suggest that ZIKV infection-induced growth arrest of human NPCs could be largely protected by abrogation of the IFN-independent ISG pathway.

Meiotic defects of the nbs-1 mutant are partially suppressed by abrogation of the nonhomologous end-joining (NHEJ) pathway, indicating a role for NBS-1 in antagonizing NHEJ during meiosis.

Strikingly, the configurations predicted by the independent reduction/removal of EVL dragging and autonomous random motility were experimentally mimicked by abrogation of E-cad function (dn E-Cad or e-cad-MO; Fig. 3e g; Supplementary Figs 4 and 5) and disruption of Rac1-mediated polarized cell protrusions (Rac1-T17N) (Figs 6h and 10j,m; Supplementary Movie 4), respectively.

To guarantee the proper balance between dose intensities, efficacy, and toxicity, triplet chemotherapy schedules could be further improved by abrogation of folinic acid and bolus 5-FU, a new and easy modality of 5-FU administration, such as timed flat-infusion 5-FU, associated with alternating irinotecan and oxaliplatin; this could favor diffusion of this intensive treatment in clinical practice.

Next, we investigated whether DIDS provided protection by abrogation of curcumin-induced nuclear AIF translocation.

The fold-induction generated by abrogation of yox1+ varies widely across the studied transcripts with a maximum of 7.4-fold for cdc18+ and a minimum of 1.6-fold for pfh1+ (Figure 2B).

This effect is mediated directly by Shh as illustrated by the abrogation of the capacity of MPsShh+ in increasing perfusion in the presence of Shh antagonist, cyclopamine.

The German period is also marked by the emancipation of the Jews that is, by the abrogation of discriminatory laws directed against them and by their partial or complete assimilation.

Ephrin receptor A2 ligand-independent activation induced by AA was also confirmed by the abrogation of activity following addition of the ligand EphrinA1-Fc.

Specifically, this apoptosis is inhibited by pharmacological abrogation of caspase 8 activity, by expression of a dominant negative mutant of the death receptor adapter protein FADD, or by expression of a dominant negative mutant of DR5.

Interestingly, the phenotype was linked to increased peripheral GH-induced lipolysis and cluster of differentiation 36 mediated hepatic uptake of FFA, which could be rescued by the abrogation of GH secretion or partially normalized by antagonistic PPAR-γ action.