Sentence examples for by abnormal gene expression from inspiring English sources
Another disorder caused by abnormal gene expression, Angelman syndrome, also is suspected of being linked to IVF.
Drug resistance has a genetic basis and it is caused by abnormal gene expression.
The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug resistance of tumor cells, which is usually caused by abnormal gene expression.
* P < 0.05, ** P < 0.01, *** P < 0.001 GMS is caused by abnormal gene expression in several developmental stages of stamen development, male gametophyte development, pollen formation, pollen nutrient support, and pollen tube elongation.
Their pathogenic behavior is driven by an abnormal gene expression profile that results from changes in signaling pathways, transcription factor activity, and a grossly altered epigenetic landscape.
This induction could be defective in cancer due to abnormal gene expression by the tumor-associated stromal cells [ 7].
Recently, SNPs were shown to cause abnormal gene expression by disrupting the interactions between miRNAs and their CDS-located binding sites, which reveal that the regulatory effects of CDS-located miRNA target sites are significantly affected by SNPs (23).
We believe that aberrant H3K9Ac in cloned mice is a critical factor influencing abnormal gene expression, but by simply looking at one tissue (such as liver in this study), or embryonic stage, or animal age, the real overall impact cannot be fully determined.
Recent studies revealed that abnormal gene expression induced by epigenetic changes, including aberrant promoter methylation and histone modification, plays a critical role in human breast Carcinogenesis.
The main correlation between the two assays is showed in Figure 2. Real-time PCR was not only used to confirm the abnormal gene expression profiles detected by microarray analysis, but also to better define fold-change variations using a more sensitive approach.
Hence, we propose that nonsynonymous SNPs could also cause abnormal gene expression or function by altering RNA secondary structure, which should be considered in functional annotation of nonsynonymous SNPs.
