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Many are single case studies, some quite anecdotal, while others are biased or characterised by a weak study design.
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Just as a weak study design can sabotage one's publication options, so can weak statistical inference.
However, the distribution of the tones, heights and annotations of the bars (studies) populating this row of the matrix suggests that the evidence for such a gradient was mostly contributed by comparatively weak study designs, some of which found a gradient only in 'intermediate' rather than 'hard' outcome measures.
A survey is a relatively weak study design.
The current findings of research are limited by weak study design and non-standardized instruments which decrease the level of evidence.
Interpretation of findings is limited by the relatively weak study design.
Fourth, RR estimates for chronic diseases and conditions resulting from alcohol consumption frequently are hampered by weak study designs that base estimates of alcohol-related risks on nonexperimental designs (i.e., case-control and cohort studies).
Systematic reviews of efforts to increase utilization of adolescent health services in LMICs, reported that the evidence was often limited by weak study design [ 14, 15], such as lack of data on process evaluations, long-term follow-up, cost-effectiveness, scale-up, and the impact on health outcomes.
However, it is important to note that previous reviews and recent studies reflect a wide range in quality of evidence with several studies limited by small sample sizes, weak study design and limited detail regarding the team-training curriculum or implementation strategy.
The field is plagued by small, weak studies that are hard to turn into statistically robust conclusions.
Poor construct validity of the Hausa IPAQ-SF in the present study is indicated by a weak, albeit significant, correlation only between rate pressure product as an index of cardiorespiratory fitness index and sitting time (Min week-1) (ρ = 0.21).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com