DOI: http://dx.doi.org/10.7554/eLife.07839.002 The myelodysplastic syndromes (MDSs) are clonal stem cell disorders characterized by ineffective hematopoiesis, morphologic dysplasia, and a variable risk of progression to acute myeloid leukemia (AML) (Elias et al., 2014).
When WHR was analyzed as a continuous variable, risk increased by 27%95%5% CI 7 50%) per 0.1 increase.
If we restrict the analysis to single cause variables, Diabetes was the most common variable, followed by Smoking, Age and the combined variable Risk Level/Risk Chart.
Notably, decreased abundance in members of the butyrate-producing Clostridial clusters IV and XIVa have been reported in the gut of inflammatory bowel disease (IBD) patients, another prevalent human disease which displays variable risk by virtue of race and ethnicity [ 55].
The diversification of herds is thus an important strategy that pastoralists use to manage and cope with risk presented by a variable climate and to reduce their vulnerability to recurrent droughts.
The individual-level coefficient, Ci is determined by the formula exp[∑βj xij - μj)], where βj is the log odds ratio (OR) of the risk conferred by a variable j, and xij refers to the value of variable j for individual.
One such assumption was that the variable risk posed by P. vivax and P. falciparum could be ignored.
The women were at variable risk of breast cancer by Gail score and 68 (49.6%) had a diagnosis of LCIS or atypical hyperplasia.
To fully clarify the virulence and its epidemiological characteristics (e.g. variable risks by age and underlying diseases), two lessons for surveillance and data sharing should be noted.
These results may indicate that the pathways by which DEHP is metabolized may impart variable risks for altered thyroid hormones, based on the proportion of DEHP that undergoes oxidative metabolism compared with the proportion that is excreted as the monoester.
