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The latent period is a constant (0.75 days) followed by a variable period (mean 0.5 days).
It has also been well established that the onset of type 2 diabetes mellitus is preceded by a variable period of abnormal glucose homeostasis, characterized by progressive insulin resistance (IR) and impairment of β-cell function [ 2].
Joffe et al. (16) proposed a scheme for the pathogenesis of type 2 diabetes in the black population of Southern Africa, in which a reduction of β-cell mass (due to childhood malnutrition and/or genetic factors), followed by an accelerated phase of β-cell decompensation induced by a variable period of peripheral insulin resistance, would ultimately lead to insulinopenic type 2 diabetes.
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Over-population and relinquishment of pet cats are ubiquitous problems worldwide, and rehoming centres (also known as rescues/ shelters) aim to ameliorate this by holding cats in confinement for a variable period until a new home is found.
In experiments 1-4, individual events (Ton) lasted for 4 frames (∼53 ms), followed by a variable blank period (Toff).
In each trial, an arrow set is presented for 2500 ms, followed by a variable fixation period of 2000 to 3000 ms. Each trial lasts 5 s on average.
Following a variable delay period [a stimulus onset asynchrony (SOA) of 900, 1100, 1300, 1500 or 1700 ms] the entire stimulus was presented for 500 ms; this was then followed by a variable response period (2700 ms – SOA for that particular trial) during which the fixation point and landing line alone remained onscreen, i.e. the spokes and pointer were extinguished.
Stimuli were presented for 2 seconds, followed by a variable fixation period of 2 10 seconds.
To characterize ETAR desensitization, cells were stimulated with a maximally effective concentration of ET-1 (50 nM, 30 s) followed by a variable washout period and a second identical application of ET-1.
Continuous infusions of analgesics and sedatives are a very effective method for avoiding the bolus medication therapies that initiate a 'peak' of therapeutic action followed by a variable 'valley' period, during which the patient receives little or no drug effect.
Each of the thermocoagulation procedures was followed by a variable attack-free period, but polytherapy was still needed since attempts at dose-lowering proved useless.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com