Sentence examples for by a validation dsRNA from inspiring English sources

Hits identified in both the initial screen and the repeat screen were more likely to be confirmed by a validation dsRNA (24/33 versus 2/7).

For 258 of the genes that scored as hits in the primary screen, we generated templates for preparing a minimally overlapping (0-11nt) validsRNAn dsRNA.

The validation dsRNAs targeted regions of the transcripts not overlapping or only minimally overlapping (<12 nucleotides) with those targeted by the dsRNA used in the initial screen.

72 (50.7%) of these validation dsRNAs confirmed the results of the primary screen (Additional File 3).

The trigger can occur naturally, as in the case of a cellular infection by a dsRNA virus, or by the intentional introduction of dsRNA to induce user-directed degradation of the cognate transcript(s).

Finally this dsRNA is diced by DCL4 into 21-nt trans-acting siRNAs (ta-siRNAs) a process assisted by a dsRNA binding protein 4 (DRB4).

Accumulation is suppressed by a GFP-targeting dsRNA (iGFPi).

Typically, RNAi is triggered by double-stranded RNAs (dsRNAs) that are cleaved into small 21 23 bp small interfering RNAs by a dsRNA-specific enzyme, and thereafter, cellular machinery that causes degradation of dsRNA-complementary endogenous mRNA is set in motion.