Sentence examples for by a unique binding from inspiring English sources
Previously, we showed that the Fn-binding MSCRAMMs, FnBPA and FnBPB from Staphylococcus aureus and Sfb1 from Streptococcus pyogenes, contain a common motif that allows these proteins to bind to the N-terminal domain (NTD) of Fn by a unique binding mechanism that we called the tandem β-zipper.
Additional layers are then created by the fact that each sgRNA can be programmed to have two recognizable loops that can be bound in homogenous or heterogeneous configurations by a unique binding protein being fused to unique effector domains [ 88].
Thus, the RAS/MAPK signaling pathway activates ETS1 and ETS2 by promoting a unique binding interface with p300 or CBP.
The present study resulted in the identification of novel "bis-statine" inhibitors shown by crystallography to have a unique binding mode.
This raises the possibility that these non-polymorphic OR may be involved in recognising odorants of particular importance or may have a unique binding specificity not shared by other OR.
Many simple motif extraction algorithms have been proposed primarily for extracting the transcription factor binding sites, where each motif consists of a unique binding site [ 4- 10] or two binding sites separated by a fixed number of gaps [ 11- 13].
Silibinin partially overlapped with the cavity occupied by other STAT3i in the SH2 domain to indirectly prevent Y705 phosphorylation, yet showing a unique binding mode.
Here, we report a unique binding specificity and mode of ligand binding for a family 32 CBM.
These effects may be modulated in part by a second unique binding site identified for hydroxytamoxifen in the coactivator-binding groove of ER β that may disrupt ER β-coactivator interactions [ 76].
In addition, synthetic RNA differing from the WT synthetic RNA by a unique probe binding region was used as IC to monitor the overall efficiency of the RT-PCR.
In contrast, nonheme FeIII coordination in nitrile hydratases (NHases) is accomplished by a unique CXXCXC binding sequence in which two cysteines are present as the sulfinic and sulfenic acid states.
