Sentence examples for by a subtle modification from inspiring English sources
Our results clearly indicate that agonism and antagonism of the antibody/cytokine receptor chimera can be readily switched by a subtle modification of the ligand binding domain as well as that of GPCRs, also implying the existence of inverse agonism in cytokine receptor superfamily.
Now a team reports that one serious side effect can be overcome by a subtle modification in the amino acid sequence of the promising drug.
Some roles of the Tβ4 and Tβ10 couple are linked to a subtle modification of their relative amounts [11].
Low level fold-change acts in favor of a subtle modification of brain gene expression, much as has been suggested for task specialization [ 41].
The action of antifungal agents is modulated by subtle modification of the membrane lipid composition [17].
Substrate specificity can be influenced by subtle modifications to a generic polymerase module [ 32] and most DNA polymerases are able to incorporate rNTPs as a substrate instead of dNTPs [ 33- 36].
This quality can be changed by very subtle modifications and needs to be considered in the interpretation of studies.
This material opens an avenue for the preparation of new functional materials by conversion of the nitrile group into amines, carboxylic acids, amino acids and chiral groups, according to the desired application, by subtle modifications in the synthetic methodology.
These fundamental differences in enzymatic activity do not arise from changes in the catalytic mechanism but rather are determined by subtle modifications in the primary sequence and structure of these proteins.
Sait Faik's subtle modification to Abasiyanik means someone whose aba is scorched, itself a figurative expression for "a person desperately in love".
