Quantitative assessment of proSP-C immunostaining by pixel counts showed a substantial difference between Cby+/+ (1,437±477) and Cby−/− (47,660±4,796) mice (P<0.001).
Taxon × light × start and taxon × collection × start were both a result of P. rhoeas exhibiting more pronounced responses to start and collection in light than in darkness, and taxon × collection × start also by P. argemone showing a substantial difference between summer and autumn collections in darkness but not in light (cf. Fig. 3 and Fig. 4).
Slowed conversion of dimethoate to its active metabolite omethoate is suggested by the lack of a substantial difference in BuChE inhibition (related to omethoate concentration) between patients ingesting and not ingesting alcohol, despite the higher concentrations of dimethoate in those with detectable alcohol.
His team was particularly surprised that although the genes of the two B clade viruses only differed by 12%, the two viruses showed a substantial difference in a critical feature: the parts of the virus that trigger killer-cell production.
The F.T.C. chairman, Timothy J. Muris, told an audience at the annual Aspen Summit of the Progress and Freedom Foundation, a free-market-oriented group, that "no one should expect any new law to make a substantial difference by itself".
Sorenstam, who had been supplanted at the top of the L.P.G.A. Tour the last two years by the Australian Karrie Webb, sees a substantial difference in her level of play these days.
The average of all scores stayed the same across the years, but individual IQ scores rose or fell by as many as 21 points, a substantial difference – enough to take a person of "average" intelligence to "gifted" status, or vice versa.
Indeed, several longitudinal mortality follow-up studies presented a substantial difference in mortality by education in South Korea [ 15, 16].
Adjusting for temperature made a substantial difference, reducing estimates by about 33% for the 3- and 7-day means and considerably more for the 31-day mean at the central site.
