Zinc may protect insulin and β-cells from being attacked by free radicals by playing a structural role of antioxidant enzymes, such as copper, zinc, and superoxide dismutase (CuZnSOD) (19, 20), by competing with redox-active transitional metals, such as iron (19, 20), or by stimulating expression of metallothionein (21), a free-radical scavenger (22).
As with α-tubulin, which binds GTP but never hydrolyzes or exchanges it, nucleotide binding by septins plays a structural role in building block assembly, but for septins this role is only necessary in certain situations.
Genes encoding to structural proteins were represented by heat shock proteins (HSP) such as HSP70 that is known for its importance for stress tolerance, and ribosomal proteins that are known to be affected by salinity and play a structural role during the stress.
Together, these results show that pre-existing perisynaptic processes intercalate between the new spines and some of their potential presynaptic partners and by doing so, may play a structural role in their connectivity by blocking the access of the spines to some of their potential partners.
In the alternative hydrolysis reaction the metal ion, Cu II), Ni II) or Pd II), plays a structural role by forming a square planar complex with Ser/Thr His or Ser/Thr Xaa His sequence, which enables a N → O rearrangement of the acyl moiety in the peptide bond downstream from the Ser/Thr residue.
The periplasmic domain plays a structural role by tethering the OM to the peptidoglycan cell wall layer.
Collagen fibrils are often described to play a structural role by forming a receptacle which can delineate the main area destined to become mineralized in bones [99], [100].
In both, boron could play a structural role by bridging hydroxyl groups.
Lamins play a structural role by assembling into the lamina network that underlies the inner nuclear membrane of the nuclear envelope (NE).
More specifically, in BtpA the WxxxE motif may play a structural role by positioning the G183 residue for interaction with microtubules.
