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This is supported by a strong binding in the case of a free accessible PSP94 (data not shown).
The nucleotide effect in the recombinant protein is confirmed by a strong binding of Py235 to RBCs in the presence of MgATP which is significantly lower in the presence of MgADP or the absence of nucleotides [27].
In the "hinge and latch model" shown in Fig. 4, Nrf2-Keap1 contact is mediated by a strong binding interaction between the ETGE motif and one Kelch domain of Keap1 (the "hinge"), and a weaker binding interaction between the DLG motif and the other Kelch domain of Keap1 (the "latch") 33, 36.
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Na+ channels compensate for this energy barrier by providing a strong binding site for Na+ in the pore; in contrast, the PSAC pore offers negligible compensation, with an Eisenman selectivity sequence that corresponds to the weakest theoretical binding site for permeating ions.
Studies have shown that FA complexes modified by carboxyl deuterogenic remained a strong binding capacity with FR [21].
According to Infrared spectrum analysis (FTIR), the Tween80 surfactant molecules bond to the surface of LiFePO4 and form an adsorption layer, which contribute to the formation of a homogeneous carbon layer tightly coating on the surface of LiFePO4 particles in the process of sintering, due to a strong binding force provided by surface chemical bonds.
We find that when a kink pair nucleates at hydrogen, the activation energy is decreased by the transition of hydrogen to a stronger binding site, while it is increased by the transition to a weaker binding site.
The rLIC12730 depicted a stronger binding by Western blotting when compared to ELISA data, while rLIC12238 showed an opposite behavior (Fig. 3A, 3B).
We interpret this as the result of a stronger binding to the receptor by brazzein than by lactisole.
Since the weak interaction of gp150 with GAGs had much greater function consequences for MHV-68 infection than the strong interaction of gp70, we conclude that GAGs do not promote infection by providing strong binding themselves, but by reversing a constitutive inhibition of cell binding imposed by gp150.
Cisplatin pharmacokinetics in the inner ear after intravenous injection is influenced by its strong binding to the plasma proteins rendering a large part of it nonactive and by the barrier systems in the cochlea, the blood-perilymph barrier, separating blood from perilymph, and the intrastrial fluid-blood barrier, separating blood from endolymph [ 15].
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