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Well-defined dendritic oligomers of poly(β,β-dibromo-4-ethynylstyrene) of the first and second generation havebeen synthesized by a stepwise synthesis, and characterized.
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This is because natural-rubber molecules, the product of a stepwise synthesis by enzymes, have a more regular structure than the artificial ones made by chemical engineering.
After swelling the resin in dichloromethane solvent for 30 min, a stepwise synthesis was initiated by removal of the Fmoc protecting group from the Rink amide resin with a solution of 20% piperidine in DMF.
The reaction is fast and specific, and is used in a stepwise synthesis to prepare trinucleoside diphosphate and tetranucleoside triphosphate.
The decrease in intensity as the chain length increases is fitted to an exponential decay curve which then allows for the determination of a stepwise synthesis yield.
Assuming a stepwise synthesis yield for probes of 95% per base and that the density of initiation sites for probe synthesis is 5 × 1017 molecules/m, the average distance between full-length 25 mer probes is about 3 nm.
A soluble chloromethylated polystyrene has been used as a support for the stepwise synthesis of oligoethers.
We have previously reported the stepwise synthesis of a safranine analogue, p-methoxy safranine.
Levine et al. used a stepwise chemical synthesis technique to create peptoid-based polyvalent constructs.
Oligonucleotide synthesis is carried out by a stepwise addition of nucleotide residues to the 5'-terminus of the growing chain until the desired sequence is assembled.
The indC gene of E. chrysanthemi codes for a non-ribosomal peptide synthetase that carries out the stepwise synthesis of the blue pigment indigoidine.
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