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Has mild to moderate GI side-effects that may be minimized by a stepwise dose regimen.
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A stepwise dose escalation was performed in order to determine the in vivo maximum tolerated dose (MTD).
A stepwise dose-reduction schedule was employed starting at the 18 Gy level with dose-reduction steps of 2 Gy each.
CDDP-resistant KB cells, KB/CDDP T), were established by stepwise dose escalation with CDDP in our laboratory.
Cisplatin (CDDP -resistant head and neCDDP -resistantlls were establisheadby stepwise dose escandtioneckth cancer
The simulation of the STP involved spiking sewage sludge with NM-300K and silver nitrate over 10 days and a shorter application by stepwise dosing of AgNPs into sewage sludge over 2 h.
This was achieved by a stepwise addition of each dose response curve until a significant difference was detected by ANOVA testing.
In this report, paclitaxel-resistant cervical cancer cells (HeLa-R cells) were induced by a stepwise selection of various doses of paclitaxel.
We have observed that mice could survive a large dose of ricin poisoning if the mice were poisoned by a stepwise increase of the ricin dose.
They can be minimised through the use of an appropriate stepwise dosing regimen and careful choice of diet.
After cells are recovered, this treatment is repeated with a stepwise increasing dose of CDDP.
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