Sentence examples for by a stepwise addition from inspiring English sources

Oligonucleotide synthesis is carried out by a stepwise addition of nucleotide residues to the 5'-terminus of the growing chain until the desired sequence is assembled.

The calibration was performed by a stepwise addition of a standard analyte solution.

This was achieved by a stepwise addition of each dose response curve until a significant difference was detected by ANOVA testing.

This was achieved by a stepwise addition of profile data with similar appearances until a significant difference was detected by the Friedman test in a similar manner as previously described with ANOVA.

Current American Diabetes Association treatment guidelines advocate starting with dietary therapy alone or monotherapy with metformin followed by a stepwise addition of further therapy after documented treatment failure (2).

It has been hypothesized that early initiation of treatment with the combination of oral anti-diabetes agents with complementary mechanisms of action can increase the durability of glycaemic control compared with metformin monotherapy followed by a stepwise addition of oral agents.

A stepwise addition of each variable was associated with a non-significant increment in ICU mortality (Fig. 2).

Fluorescence readings were taken following a stepwise addition of VGD solutions.

The VERIFY study is a 5-year three-period study (Fig. 1) designed to compare early initiation of a vildagliptin metformin combination with standard-of-care initiation of metformin monotherapy (period 1), followed by the stepwise addition of a second oral anti-diabetic agent (period 2).

The titration of mouse Nat2 with bisphenol A was carried out by stepwise addition of small volumes (5 20 μL) of a concentrated solution of bisphenol A (100 mM in deuterated DMSO) to the mouse Nat2 solution in the NMR tube.

In ML bootstrap analyses, heuristic tree searches were performed from a single parsimony tree estimated by random stepwise addition per replicate.