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Important differences between the two groups were defined by a standardised difference exceeding 0.1.
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The difference between group means divided by the SD is called a standardised difference (or Cohen's D value [ 2]) and allows estimation of power based on a t test.
Based on the 14 participants in the smaller group (CWD), a power of 80%% (β = 0.2) was provided by the sample size to detect a standardised difference (Cohen's d) between the CWD and the Con groups of 1.3 given the α-value of.05.
A standardised difference of <0.1, by convention, is considered to indicate good balance of groups on that variable.
12 The balance of the covariates before and after matching was assessed using a standardised difference since, unlike significance testing, it is not confounded by sample size.
19 We presented standardised differences as a summary measure of differences between groups; we calculated a standardised difference as the difference between the sample means (or proportions), divided by the pooled standard deviation.
Figure 3 shows the difference between a percentage placebo effect and a standardised difference.
55 We estimated standardised differences for all covariates before and after matching, with a standardised difference of 10% or more considered indicative of imbalance.
It has been suggested that a standardised difference of less than 10% represents meaningful balance.
Absolute standardised differences were estimated to evaluate the pre-match and post-match imbalance, and a standardised difference <0.1 was considered a negligible difference in the mean or prevalence of a covariate between treatment groups (Fig. 1) [ 23, 24].
Overall, electrical stimulation increased strength by a standardised mean difference (SMD) of 0.47 (95% CI 0.26 to 0.68) and this effect was maintained beyond the intervention period (SMD 0.33, 95% CI 0.07 to 0.60).
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