Suggestions(2)
Exact(2)
A standard dose followed by a standard dose booster did not consistently improve these endpoint measures.
Subsequent reports have, however, suggested that delay does decrease tumour yields, and this is confirmed by the present study of 2200 mice initiated at 8, 48, or 68 weeks with 10, 30, 100, or 300 microgram of DMBA and promoted by a standard dose of TPA for 15 weeks, after various delays.
Similar(58)
With single interventions, internal validity is maximised by having a standard dose delivered in the same way at each trial site.
OGTT was performed after a minimum of 8 hours overnight fasting, by orally administering a standard dose of 75 g anhydrous glucose dissolved in water.
The echo signals from the blood can be enhanced up to a 1000-fold by injection of a standard dose of microbubbles, which allows direct visualization of flow in vessels down to 50 µm.
Here we report a phase I study evaluating the combination of escalating doses of BMS-188797 as a 1-h infusion followed by cisplatin at a standard dose of 75 mg m−2 given every 3 weeks in patients with advanced solid tumours.
24 According to the definition of CVR, the change in blood flow would be standardised by the administration of a standard dose of acetazolamide.
Pulse HVHF (PHVHF) is a different approach that may offer the most efficient results: it consists of a daily schedule of 6 to 8 hours at a pre-dilution replacement rate of 85 ml/kg/h followed by standard CVVH at a standard dose of 35 ml/kg/h [ 19].
In mice with a larger dose of fluorescein injected, background luminescence increases by about 1500%, while with a standard dose, fluorescence only increases by 10%.
A meta-analysis 27 found that blood pressure lowering drugs can reduce systolic blood pressure by 9.1 mm Hg at a standard dose and 7.1 mm Hg at a half dose.
44 A randomized trial by the Nordic Neuro-Oncology Group comparing RT with a standard dose of TMZ is ongoing.
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