Sentence examples for by a specific protease from inspiring English sources

It is known that mammalian IGFBP-4, but not IGFBP-1, is cleaved by a specific protease, pregnancy associated plasma protease (PAPP -A, and that the PAPP -Acleandge sithats locathe in the L-domain of all known IGFBPAPP-A19], [20], [21], [22].

Presumably there has been strong selection pressure to ensure processing of the propeptide by a specific protease.

Posttranslational processing of the precursor protein F0 into infective F protein cleaved by a specific protease only exists in avian cells [ 36].

Because PCT is cleaved in the gland by a specific protease, circulating levels are very low (< 0.1 ng/ml) in healthy individuals.

Compared with KSI fusion proteins, GST fusion proteins could be relatively easily solubilized and refolded in detergent micelles, facilitating the cleavage by a specific protease to release the passenger protein prior to further purification [ 10, 22].

TA systems are regulated at transcriptional level by the antitoxin and/or the antitoxin-toxin complex, and this antitoxin is continuously degraded by a specific protease present in the cytosol of the bacterium.

Interestingly, a specific fragment migrating at about 48 kD in SDS-PAGE was detected when hnRNP K was enriched by immunoprecipitation, indicating that a specific protease cleaves the protein.

Other investigators have also recently reported upregulation of proteolytic enzymes by TNF- α in murine bone marrow cells and have also demonstrated increased in vitro degradation of bone collagen following TNF- α stimulation of osteoclasts that was successfully inhibited by the addition of a specific protease inhibitor (Katunuma et al, 2002).

A degradation of the larger MAVS isoform occurred following SeV H4, but not WT, infection, implying that MAVS is not cleaved by a specific SeV protease.

Besides, it has been reported that after endosomal uptake of nanomaterials, conjugated or non-specifically bound proteins degrades rapidly by a low-specific protease Cathepsin L, leading to significant loss of function of bio-conjugated particles.

This is usually done by engineering a cleavage site between the tag and the encoded protein that is recognised by a site-specific protease, such as the one from tobacco etch virus (TEV).