Sentence examples for by a specific binding from inspiring English sources

Such peptides, also called antigens or epitopes, are identified by a specific binding to elements of a library or repertoire of unique proteins called receptors (e.g. antibodies or T cell receptors).

Each MHC class I molecule, whose total number surpasses the thousands of alleles to date [5], is characterized by a specific binding motif that is possible to "decode".

Based upon the above schematization, the population of T cells can be thought of as composed by different phenotypes corresponding to the different TCRs and the virus populations as characterized by a specific binding ability.

In our study (Oehlmann et al. 2006), we did not intend to deliver a complete binding study in which saturation experiments with Scatchard analysis are needed, but to provide indications for the presence of estrogen receptors by a specific binding of ligands to cytosolic extracts (a widely used practice).

Even though tumour EGFR expression measured by IHC has never been shown to be predictive of anti-EGFR monoclonal antibody (mAb) efficacy, the fact that dMMR tumours tend to express elevated EGFR levels measured by a specific binding assay, and are prone to be KRAS wt, suggests that the impact of MMR status on the efficacy of anti-EGFR mAb should be explored more thoroughly.

In general additional modules fused to a catalytic domain may play a role in substrate specificity by providing a specific binding site or shaping the active site to recognize a substrate with a different shape or size [40].

These results were confirmed by detecting a specific binding of the same mAbs to CHO cell transfected with a TfRC expression plasmid (data not shown).

Chk2 is phosphorylated on Thr-68, which thereby promotes the oligomerization of Chk2 by creating a specific binding site for the FHA domain of another Chk2 molecule.

Therefore, it is possible that the disordered binding regions may play a passive regulatory role by providing a specific binding site, where IDRs serve as the identification sites of the protein to be regulated [ 13, 51].

Various compounds such as amino acids, sugars, and polyethylene glycols were shown to activate MtrB, presumably not by binding to a specific binding site, but by changing the hydration state of MtrB.

This is, to our knowledge, the first report that identifies poly P in the cell wall of any plant species by direct labelling with a specific binding protein or by biochemical quantification.