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For some genes there are multiple probes, although 87% of the genes are targeted by a single probe.
For those annotation units represented by a single probe, only 3 ratios (for each probe) were available for the down-stream calculation of T-statistics and F-statistics.
In this dataset, AHR, EGR1 and HIF1A were each represented by a single probe and all of them showed significantly higher correlations with response (Fig. 3B).
As the probe length increases, so does the number of probes, |Ll|, in the library (Figure 1); as more sites of variation are covered by a single probe, potentially this could be a combinatorial expansion [17].
These limitations can be addressed by a post-PCR, probe-based fluorescence melting curve analysis (FMCA) procedure that allows detection of multiple mutations by a single probe based on melting temperature (Tm) shifts [6].
Mice were tested under a standard protocol (6 days training, with 4 trials a day, to a single platform position, followed on day 7 by a single probe trial).
Similar(28)
Frankly, I am more excited about the richness of information that could come from comparisons among probes that interact differently with membrane lipids (as revealed by Fig. 5) than by choosing a single probe based on the concept that two different measurements with the probe are best if they are redundant.
Thus, they demonstrated the feasibility of ABL typing by using a single probe.
In our case the average number of probes present per probe-set at an optimum CDF value of 550 was 2.0, with a total of 16,416 probe-sets being represented by a single probe-pair.
Often, different conformers of the same molecule co-exist but may not be individually identifiable by a single probing technique [ 35].
Because some genes are recognized by more than a single probe set, each of which is characterized by an individual specificity and sensitivity that differently contribute to the gene expression value, prior to the analysis, a mean gene expression value was calculated after weighting each probe set for its own sensitivity and specificity.
More suggestions(18)
by a single survey
by a single catheter
by a single detector
by a single percentage
by a single umpire
by a single anecdote
by a single vote
by a single mom
by a single run
by a single employer
by a single lawyer
by a criminal probe
by a positive probe
by a single light
by a weak probe
by a single sentence
by a double probe
by a federal probe
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com