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Both arrangements differ from AAGO by a single inversion of the trnS1-rns region (fig. 2).
In this section, we address the question whether stratum 3 was formed by a single inversion on the Y chromosome.
Roper et al. [ 8] noted that this gene order change is not caused by a single inversion.
For concreteness, consider the case of a test genome that differs from the reference genome by a single inversion with breakpoints a and b (Fig. 1A) that fuse at a single coordinate ζ in the test genome.
A dot-plot of the relative location of TCS orthologues in the two genomes (Fig. 4a) recapitulated the global synteny observed between Mx and Mf, which is dominated by a single inversion [ 26].
Chromosome arm XR differs by a single inversion between D. pseudoobscura and D. persimilis, and the breakpoints of this inversion have been mapped (Noor et al. 2007; Bhutkar et al. 2008).
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The simplest comparison is that of FG5 and PG5, which display remarkable levels of structural conservation, the marker order between Prunus and Fragaria differing by just a single inversion event.
For PCGs and rRNAs, the gene arrangement of the chiton Katharina tunicata[ 32] is also shared by Haliotis, a primitive gastropod [ 33]; a single inversion separates it from the gene arrangement of Caenogastropoda (with the exception of D. gregarium; see [ 15, 34]); few steps are required to transform the gene order of Katharina in that of Nautilus, a primitive cephalopod [ 35].
Either they both underwent inversions independently or there was a single inversion involving both genes, followed by a transposition.
The discrepancy was reconciled by assuming just one inversion: here, complex 165 (analogous to 161), instead of undergoing the Br− initiated inversion, is believed to coordinate CuBr2 (167), and Pd itself then serves as a leaving group in the ring closure,[ 72] so that 168 is formed with a single inversion.
A single inversion of gene order has occurred in the mammalian clade.
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