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As shown in our LPS animals, tissue perfusion was characterized by a severe decrease of MFI and PVD concluding that all the determinants of tissue oxygenation were compromised.
Alpha-1 antitrypsin (AAT) deficiency is a hereditary disorder characterized by a severe decrease in AAT plasma level, which leads to progressive liver dysfunction; however, human MSC-Heps can be AAT genetically modified as a novel paradigm of coupling cell therapy for this disease (Ghaedi et al., 2010).
This was further confirmed by a severe decrease of mitochondrial subunits (immunoblotting) and assembled complexes (BN-PAGE).
bm1 is caused by a severe decrease in CAD enzyme activity, possibly resulting from a decrease in CAD transcription [ 9, 13], bm3 is caused by a knock-out mutation in the COMT gene [ 14, 15], while the genes underlying the bm2 and bm4 mutations are unknown.
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The robust signal of less precipitation and higher temperatures that is projected by climate simulations results to a severe decrease of local water resources which can be mitigated by a number of actions.
Censure by the ORI usually results in a severe decrease in productivity, in many cases causing a permanent cessation of publication.
In fact, as we can infer by the survival functions, TNBC experienced a severe decrease in their outcome before 48 months, a curve shape that overlaps with the one draw by the NPI in those patients.
Before the initiation of ECLS support, a severe decrease in cardiac contractility was documented by echocardiography in 14 cases.
Of those, 88percentt reported a "severe decrease" in business during the last quarter.
"As a consequence of reduced activity in the oil industry, SAS has experienced a severe decrease in demand and thus passenger loads on the Stavanger-Houston route.
The survey said that 69percentt of the merchants reported a severe decrease in business in the fourth quarter, and 28percentt a modest decline.
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CEO of Professional Science Editing for Scientists @ prosciediting.com