The predictive value for a severe course of CAP, defined by death, admission to ICU or mechanical ventilation, was lower than that of the CRB-65 score.
Our patient presented with major risk factors (regular alcohol consumption and older age) for a severe course of HEV, which were identified by Péron et al. [ 3].
Symptomatically, the disease ranges from a mild attack to a severe course that commences suddenly and ends in death caused by dehydration and poisoning by bacterial toxins.
A severe course of CAP was observed in 105 (10.5%) patients.
Sepsis is characterized by a fulminant, severe course, complex diagnostics, and a high case fatality rate.
Namely, alcohol dependence can be divided into several clinically and etiologically different subgroups, the main divisions being the Type 1 alcoholism characterized with later onset and little or no antisocial behavior, and Type 2 alcoholism, illustrated by an early onset, and a more severe course with higher levels of alcohol-related problems (Cloninger, 1987).
We calculated from the logistic regression model that a 15-year lag time decreased the probability of having a subsequent severe course by approximately 20%.
Over the period of the history of combustiology one of the main problems for treatment of patients with burns is infection, both local - bacterial pneumonia - and generalized - sepsis - characterized by extremely severe course, complex diagnostics and high lethality rate.
It has been suggested that ciprofloxacin-resistant Campylobacter isolates might cause a more severe disease [ 31– 33], but we have shown opposite results and even reported that isolates highly susceptible to ciprofloxacin (MIC, 0.06 0.25 mg/L) seem to cause a more severe course of disease, characterized by more frequent bloody stools and need for hospitalization [ 15].
