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Our analysis of the amphioxus SoxB1 genes indicated that amphioxus SoxB1a probably evolved from a SoxB2 duplicate generated by a segmental duplication that produced an additional SoxB1/B2 cluster, and gained the SoxB1 characteristics through convergent evolution with SoxB1b.
Interestingly, the KLLA0B05269g gene is flanked in its distal side by a segmental duplication of 5.5 kb with chromosome D (Figure 3A).
Therefore, a local duplication followed by a segmental duplication possibly occurred.
Thus, the artiodactyl-specific genes for Ast1 and BTC1_14RD appear to have been created by a segmental duplication.
The GSTM1 deletion is located in a region of high sequence homology neighbored by a segmental duplication and this might explain that its breakpoints may slightly vary and, thus, the difficulties of calling.
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Although trace reads of this novel duplicate are found in the repository of the A. gambiae genome (as well as in those of M- and S-forms), the annotation and localization of this copy on the genome map is probably hindered by the presence of a segmental duplication which complicates the assembly.
This indicates that perforin could have originated from a segmental duplication by uneven crossing-over in the region of the MPEG1 gene.
This suggests that two single-gene duplications, followed by a small segmental duplication, occurred before the divergence of human and mouse approximately 80 million years ago.
The segments were shown to be associated "in mirror" in the proviral form of GiBV and GfBV as shown in the legend of Figure 2B [ 6] and were most probably produced by a mirror segmental duplication which occurred before the separation of Cotesia and Glyptapanteles lineages.
The whole module encoded by an operon could duplicate by means of a single, segmental duplication.
Four major mechanisms appear to be involved in PTP diversification; segments have been duplicated (i) by segmental duplication or (ii) by reintegration in the wasp genome, individual genes have been duplicated (iii) in tandem or (iv) dispersed.
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