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That event was followed by a second outbreak a week later in Kowloon Park, also in Hong Kong (4 ).
In January 2009 Nepal faced the first localized outbreak of highly pathogenic avian influenza (AI) among poultry, followed by a second outbreak in another area in February of the same year [ 1, 2], but no human cases were registered [ 3].
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This cluster arose at two separate time periods, with the first outbreak starting in the fall of 1995, peaking in 1996 and disappearing by the spring of 1999, with a second outbreak rapidly appearing in the fall of 2001, peaking in the summer of 2002, and disappearing in the spring of 2003.
Subsequent to this initial 2-year lull in reproduction, wolf numbers recovered strongly: by the second outbreak in 2010, wolf numbers and wolf density in Sanetti had surpassed pre-CDV outbreak levels.
The second outbreak was caused by an M1-type strain, the most common isolate type in Canada, which may be more virulent than other serotypes (21, 22 ).
The first outbreak caused by DENV-2 occurred in northwestern Argentina in 1998; the second outbreak caused by DENV-1 occurred in the north-northeastern part of the country in 2000.
In the second outbreak, cheeses produced by plant B were sold at a farmers' market on Vancouver Island on September 6 , 2002 and linked to a cluster of five illnesses within a family with rapid onset (<24 hrs) of severe febrile diarrhoea requiring hospitalization.
Enhanced pathogenic potential of all avian and human influenza virus isolates from the second outbreak was shown by mutation E627K in the PB2 region.
It did not publicly inform of the outbreak, which was confirmed by a second test, until Friday.
My family was devastated by this first outbreak and how it weakened me, both physically and psychologically.
AI spread to Gyunggi about a month after the first outbreak and eventually, by Day 44, most of the provinces in South Korea had reported outbreaks of the H5N1 infection.
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