Sentence examples for by a robust increase from inspiring English sources

Moreover, transient Akt-activating phosphorylation of nNOS Ser1417 [38] was followed by a robust increase in CaMKII-mediated inactivating phosphorylation of nNOS Ser847 [57].

However, TO at the pseudoglandular stage initially increased LW/BW by 15% followed by a robust increase (50%) in the later stages.

The tumour polyamine pool seems to be maintained at higher levels by a robust increase in ODC activity not properly balanced by a severe increase in SSAT activity.

In keeping with the findings on the role of dysregulated miR-29 in cardiac fibrosis, we also observed that even a minimal decrease in miRNA expression was accompanied by a robust increase in its target gene expression.

Changes in gene expression characteristic for various forms of senescence are accompanied by a robust increase of mRNA and secretion of numerous cytokines, chemokines, growth factors and proteases [ 18- 25].

In 24 month old animals, a non-significant 25%% loss (p = 0.074) of α-motor neurons in the anterior horn (Additional file 1: Figure S7) was accompanied by a robust increase in astrogliosis in the TDP-43Q331K transgenic animals compared to their non-transgenic and TDP-43WT aged –matched littermates.

Gut et al. confirmed that the Tg pck1 Luc2) line faithfully recapitulates the endogenous regulation of Pepck expression in mammals by demonstrating a robust increase in bioluminescence in Tg pck1 Luc2) zebrafish in the fasting state and the appropriate response to pharmacological modulation.

Our studies showed that short incubation with dmPGE2 altered the molecular and functional properties of human UCB T cells by inducing a robust increase of cAMP via EP2 and EP4 receptors and activating a cascade of signaling events, which resulted in inactivating phosphorylation of GSK3β, stabilization of β-catenin and TCF/LEF-mediated gene expression.

The results of this study illustrate that experimental inflammation induced by typhoid vaccination produces a robust increase in pro-inflammatory cytokines (IL-6) and reduction in a composite measure of mood (that includes both cognitive-mood and neurovegetative contributions) in normal healthy male volunteers at 3 hours.

Moreover, the effect of ATPA was concentration-dependent, with no significant effect for 0.03 µM, a moderate but significant effect for 0.3 µM and a robust increase by 3 µM ATPA applied to the recording bath (Figure 4D).

These data therefore show that the increase in CA1 pyramidal cell excitability caused by M1R activation results in a robust increase in spike output of CA1 pyramidal neurons.