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However, the advantage of resection over radiochemotherapy has not yet been confirmed by a randomized trial.
The critics are right - if they're talking about innovations like the da Vinci robot, which costs more than a million dollars and yet has never been shown by a randomized trial to improve the outcomes of prostate surgery.
These results were challenged by a randomized trial that included 70 patients with septic shock [38] and failed to show any difference in the evolution of the microcirculation with nitroglycerin compared to placebo.
This was however not confirmed by a randomized trial [ 9, 10].
The efficacy of ablation therapy as first-line therapy vs. AADs would be best answered by a randomized trial.
This can only be answered by a randomized trial with a long-term follow-up (over several years) [ 33].
Similar(45)
By contrast, a randomized trial with small sample size showed that nifekalant was inferior to amiodarone in either initial resuscitation or survival outcomes [ 21].
The first exposure principle is supported by theories of causal inference that hold that causality can only be assessed by either a randomized trial or an observational study that closely mimics a randomized trial.
Haanen C, Peetermans N, Cauchie C, Michel J, Strijckmans P, Mathe G et al. Treatment of polycythemia vera by radiophosphorous or busulphan: a randomized trial.
In a randomized trial by Marx et al. [20], HBO group had a 5.4%% incidence of ORN, as compared with 29.9 % in the penicillin group.
A randomized trial by Shetty et al. [14] comparing metallic staple versus running vicryl suture closure in hip fractures did show a statistically significant difference in infection rate favoring suture closure.
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