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If θ can be measured, the probability that the average fitness is increased by a random mutant is independent of the payoff distribution according to Eq. (5).
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A random mutant library was generated by error-prone PCR and screened for inactivating amino acid substitutions.
They employed a modified DE with a more exploitative mutation strategy and a random mutant factor.
A random mutant library of L. monocytogenes strain EGD Pkp1 was established as described recently [ 12].
The ability of human P450 1A2 to catalyze 7-methoxyresorufin O -demethylation was improved by screening of random mutant libraries (expressed in Escherichia coli ) on the basis of 7-methoxyresorufin 7-methoxyresorufin O-demethylation O-demethylation
In higher plants, disrupted individual genes are usually obtained by screening of random mutants and the probability of altering a specific gene depends very much on the size of the target sequence.
By screening 400 clones from random mutant libraries for enhanced fibrinolytic activity, two mutants were obtained: N111R, R230G.
In line with these considerations, we isolated chlamydomonas strains tolerant to ionizing radiation by exposures of different D1 random mutant libraries to radical-generating proton or neutron sources with energies similar to those occurring in space.
The draw will be performed by a random computer process.
The order was selected earlier by a random drawing.
The random orientation in the 2-D plane (0∼2π) is determined by a random number generator.
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