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These results questioned the results of Schrimsher and Taylor who proposed, based on kinetic and inhibitor studies, that NADH binds first followed by a random binding of L-arginine and pyruvate [12].
Matsuoka and Srere speculated that their findings may be explained by the existence of cooperativity in ACCOA binding or by a random binding mechanism.
This mechanism is characterized by a random binding of the two substrates that form individual binary complexes and that finally result in ternary complex formation.
Similar(55)
The final binding preference of each TF is made by taking a vote among these six binding preferences, and again in case of a tie random binding preference is assigned.
The utility of the approach is demonstrated by (i) separating known similar binding site pairs from random binding site pairs and (ii) a bioisosteric replacement study for fragments binding to subpockets of different proteins.
These distributions are significantly different from a uniform distribution that would be expected for random binding sites.
The draw will be performed by a random computer process.
The order was selected earlier by a random drawing.
Maybe by a random bullet meant for someone else.
The random orientation in the 2-D plane (0∼2π) is determined by a random number generator.
※ Pooled data by a random effect model.
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CEO of Professional Science Editing for Scientists @ prosciediting.com