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Every envelope contained a number by a random allocation process using a computer-generated random block design.
The study had a randomized, controlled, double-blind, parallel design and consisted of two phases; an initial weight reduction period of 6 weeks using a calorie-restricted diet, VLCD, followed by a random allocation to a test or control weight maintenance treatment period of 12 weeks.
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Cohen's Kappa coefficient is designed to measure the agreement between two classification methods, but it is commonly used to measure model performance by comparing a classifier with a random allocation of patients among the decision classes.
A random allocation algorithm was created by a consultant statistician using Stata software.
Random blocks of four and six were chosen and random numbers were generated using a random allocation software program [ 24] by an external researcher not involved in the study.
Participants were randomized by an online random allocation sequence generated by the EMMES Corporation and accessed by the study nurse coordinator.
Randomisation was performed by a computer random allocation program.
Pregnant women at risk of PPD (evaluated by validated interview) and their partners were randomly assigned to a control group (CG) or an experimental group (EG) by a random sampling allocation sequence.
Participants were assigned by independent random allocation by a second researcher not involved in recruitment, using a computerised random number generator, to an intervention (self-help manual plus standard care and treatment) or a control (standard care and treatment) group.
Since the model profiles are selected by the software by random allocation, independent of the data, the algorithm then determines which profiles have a statistically significant higher number of genes assigned using a permutation test.
Equal randomization to one of the two treatment was done by a computer-generated random allocation of envelopes numbered 1 to 400 and containing the letter 'A' or 'B'.
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