To investigate the use of nebulized 3% hypertonic saline (HS) for treating viral bronchiolitis in moderately ill hospitalized infants by a prospective, randomized, double-blinded, controlled, multicenter trial.
4 The current findings should be confirmed by a prospective, randomized controlled trial in older patients.
47– 49 This view is supported by a prospective, randomized trial comparing percutaneous pinning with conservative treatment in 57 patients aged over 60 years with unstable, extra-articular fractures of the distal radius.
Objective: To evaluate the efficacy of inhaled albuterol for treatment of hyperkalemia in premature neonates by conducting a prospective, randomized placebo-controlled and double-blinded clinical trial.
This is further supported by the findings from a prospective, randomized, blinded trial by Swärd et al., who showed that infusion of ANP enhanced renal excretory function, decreased the probability of dialysis and improved dialysis-free survival in early, ischemic AKI after complicated cardiac surgery [ 40].
A prospective, randomized, nested by church, design will be used to evaluate the faith-enhanced DPP as compared to a standard DPP on weight, diabetes and cardiovascular risk, over a 16-week intervention and 10-month follow up.
The benefit of this colloid osmotic agent, derived from maltodextrin, has been recently evaluated by Paniagua et al. in a prospective, randomized controlled trial in 60 diabetic patients undergoing PD [ 28].
To evaluate the impact on survival and on tumour growth of megestrol (progestin drug acting at post-receptorial level) we enrolled 45 patients with HCC characterized by variant liver oestrogen receptors in a prospective, randomized study with megestrol vs. placebo.
A prospective, randomized, controlled trial by Peruzzi showed a marked reduction in the volume of blood discarded daily: 96 ml in the conventional arm compared with 5 ml in patients with the conservation device during the mean study period of 4 days.
However, it is worth noting that only the multicenter study by Vanky et al. (6) was a prospective, randomized, controlled trial, in which no metformin effect in preventing GDM was found.
A prospective randomized controlled trial by the Canadian Orthopaedic Trauma Society compared plate and screw fixation with nonoperative treatment for displaced middle-third clavicle fractures [ 1].
