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The model here introduced as Grammatical-Restrained Hidden Conditional Random Field (GRHCRF), separates the states from the labels and restricts the accepted predictions only to those allowed by a predefined grammar.
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Sequences can be filtered by their length, quality scores, GC content, number or percentage of ambiguous base N, non-IUPAC characters for nucleic acids, number of sequences, sequence duplicates, sequence complexity (for example, to remove simple repeat sequences such as ATATATATAT), and custom filters defined by the user given a predefined grammar.
These predefined grammars are sets of rules or guidelines developed to refer to a compound with a unique textual representation (systematic term or identifier).
The percentage deductible is triggered by a predefined event.
Then the beliefs of each pixel are assigned by a predefined scheme.
The routing pipe in VBF is determined by a predefined radius.
During each iteration, each user increases his transmission rate by a predefined amount.
The definitions are expressed in XML format, which itself is constrained by a predefined XML Schema.
Therefore, the classification of reported thromboembolic events has to be done by a predefined algorithm.
Two authors performed independent data extraction by using a predefined data template.
We searched electronic health care databases and sources of gray literature by using a predefined strategy.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com