Sentence examples for by a postsynaptic modification from inspiring English sources
This potentiation was limited to dopaminergic neurons, and appeared to be expressed by a postsynaptic modification.
Memantine decreases the tonic NMDA current and galantamine enhances the action potential mediated by a postsynaptic NMDA current.
In wild-type, each presynaptic Brp punctum is apposed by a postsynaptic GluRIIC punctum (Figure 3A C).
Consistent with the results from the binding studies described here, RDX reduced sIPSCs by a postsynaptic action on GABAA receptors.
Such a presynaptic effect associated with postsynaptic modifications is not new, since the NMJ function displays homeostasis, and that decrease in postsynaptic responsiveness is often associated to increase in neurotransmitter release and vice-versa in order to maintain constant EJCs [60].
These postsynaptic modifications were apparently not due to a lack of innervation, since the dilute just as the control muscles exhibited clear presynaptic terminals and responded to nerve stimulation with contraction.
Finally, a variation of normalized EPSC amplitude without any variation of normalized CV−2 indicates postsynaptic modifications since only q can vary.
In theory this could be achieved by other mechanisms; however, our model was in fact inspired by the experimental observation that the presynaptic modifications are bidirectional (expressing both LTP and LTD) while the postsynaptic modifications are not (and express only LTP), at least on the timescale of whole-cell recording experiments.
These results suggest that the increased AMPA/NMDA ratio reflected a postsynaptic rather than a presynaptic modification.
Caffeine inhibited currents activated by exogenous glutamate and quantal events by a similar amount confirming a postsynaptic action.
Unified model of pre- and postsynaptically expressed STDP. (A ) The synaptic weight is the product of a presynaptic factor P and a postsynaptic factor q. Long-term modifications in P and q are governed by interactions between the pre- and postsynaptic spike trains.
