Sentence examples for by a null sensor from inspiring English sources
For example, a total current response detected by a glutamate sensor in the NAc core during 3 min tail-pinch was mimicked 95% by a null sensor.
As can be seen in panel (A), a brief auditory signal (75 dB, 0.25 s) induced a rapid rise in currents detected by glucose sensors with no changes detected by null sensor.
Our estimates of NAc levels made by comparison of currents detected by glucose and null sensors in rats under quiet resting conditions in two independent studies were: 664 ± 170 μM and 878 ± 55 μM.
These values are also close to electrochemical estimates of basal levels of extracellular glucose in the neighboring striatum (∼350 μM). Figure 2 shows mean changes in electrochemical currents detected by glucose and null sensors and resulting changes in NAc glucose concentration induced by several sensory stimuli of different duration and complexity.
In addition, the difference in background currents detected by active and null sensors in vivo under identical conditions may also allow an estimate of basal levels of neurochemicals, a measure rarely achievable in most electrochemical studies.
Therefore, identifying the difference between currents generated by active and null sensors under identical conditions greatly minimizes the influence of nonspecific interferents, improving reliability of neurochemical measurements.
These values in good agreement with microdialysis estimates, suggesting glucose is indeed the major contributor to the difference in electrochemical currents detected by glucose and null sensors under physiologically relevant conditions.
The null sensor shares the same construction as the active sensor, but lacks the specific enzyme that reacts with the target molecule to yield a detectable electroactive compound.
Null sensors are prepared identically to glucose sensors except for the absence of glucose oxidase.
