Sentence examples for by a mouse model from inspiring English sources

TLR4 could be the key player linking PAF-AH up-regulation to aβ2GPI IgG antibodies in APS, as evidenced by a mouse model of preterm delivery which demonstrated that PAF effects and signalling depend upon TLR4 stimulation [21].

Direct involvement of IFNγ+CD4+ T cells in TB IRIS development is confirmed by a mouse model, wherein the human disease has been mimicked by adoptively transferring naïve CD4+ T cells into M. avium-infected, T cell-deficient (TCRα−/−) mice [5].

A direct role for changes in processing activity in cancer is supported by a mouse model of lung cancer where heterozygous loss of Dicer promotes tumor progression [30].

In a recent study, the role of DLC1 as a bona fide tumor suppressor in HCC was confirmed by a mouse model with a liver-specific, short-hairpin RNA-mediated DLC1 knockdown [32].

The role in skeleletal homeostasis and cartilage development is strengthened by a mouse model with functional inactivation [ 27].

This definition can be almost fulfilled by a mouse model of heatstroke used in the present study.

Bomsztyk et al. give insights into how epigenetic modifications are involved by using a mouse model of MODS induced by acute lung injury by Staphylococcus aureus.

In addition, we examined the antioxidant activity of ISS and its antiasthmatic effects by using a mouse model of asthma induced by ovalbumin (OVA) in vivo to investigate the mechanism underlying the effectiveness of ISS in the treatment of asthma.

We have previously studied some mechanisms of spinal plasticity involving BDNF, Shh, Notch-1, Numb, and Noggin, by using a mouse model of motoneuron depletion induced by cholera toxin-B saporin.

We have previously studied some mechanisms of SC plasticity, by using a mouse model of motoneuron depletion induced by intramuscular injection of the retrogradely transported, ribosome-inactivating toxin, cholera toxin-B saporin (CTB-SAP) [ 7– 10].

By creating a mouse model that mirrors the human disease and by studying the muscle, brain, bone and other organs in the mice, we hope to be able to understand the enormous clinical variability in IBMPFD patients.